General Information

  • ID:  hor002516
  • Uniprot ID:  NA
  • Protein name:  tuftsin
  • Gene name:  NA
  • Organism:  NA
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  TKPR
  • Length:  4
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Analgesic effect
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002516_AF2.pdbhor002516_ESM.pdb

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Physical Information

Mass: 55428 Formula: C21H40N8O6
Absent amino acids: ACDEFGHILMNQSVWY Common amino acids: KPRT
pI: 11.65 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 0
Hydrophobicity: -267.5 Boman Index: -2304
Half-Life: 7.2 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 0
Instability Index: -3020 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  1711198
  • Title:  Antinociceptive Action of the SP1-4 Tetrapeptide and of Some Tuftsin Analogs